Developmental Expression of Protein Phosphatase 2A in the Kidney
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منابع مشابه
the effect of e-64 on the developmental competence of sheep cocs during in vitro maturation
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Protein Phosphatase 2A (PP2A) plays an essential role in many aspects of cellular physiology. The PP2A holoenzyme consists of a heterodimeric core enzyme, which comprises a scaffolding subunit and a catalytic subunit, and a variable regulatory subunit. Here we report the crystal structure of the heterotrimeric PP2A holoenzyme involving the regulatory subunit B'/B56/PR61. Surprisingly, the B'/PR...
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Protein phosphatase 2A (PP2A) is a large family of enzymes that account for the majority of brain Ser/Thr phosphatase activity. While PP2A enzymes collectively modulate most cellular processes, sophisticated regulatory mechanisms are ultimately responsible for ensuring isoform-specific substrate specificity. Of particular interest to the Alzheimer's disease (AD) field, alterations in PP2A regul...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 1999
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v1081737